Kaley Cuoco is incredibly popular due to her role as Penny on The Big Bang Theory, but the actress has had a long and diverse career in the entertainment industry. Before landing the iconic role that made her a household name, Cuoco began her acting journey at a young age, appearing in various commercials and small television roles. Her breakthrough came in 2002, when she joined the cast of the hit sitcom 8 Simple Rules, where she showcased her witty sense of humor and charm.

14 Kaley Cuoco As Ava Bartlett In Based On A True Story (2023)

Kaley Cuoco stars as Ava Bartlett in the comedy thriller, Based On A True Story. Ava, a realtor struggling to land the big deals by day and a true crime junkie by night, finds herself caught up in a real-life mystery that blurs the lines between fiction and reality.

13 Kaley Cuoco As Anne In The Man From Toronto (2022)

Kaley Cuoco shines in her role as Anne in The Man From Toronto. With her natural charisma and comedic timing, Cuoco brings a delightful energy to the film. As Anne, she portrays a strong and independent woman who is not afraid to speak her mind. Cuoco's chemistry with the other actors, especially her co-star Kevin Hart, is palpable on screen. Together, they create a dynamic duo that keeps the audience entertained and laughing throughout the movie. Cuoco's portrayal of Anne adds depth and dimension to the character, making her more than just a sidekick or love interest.

12 Kaley Cuoco As Sheila In Meet Cute (2022)

In the heartwarming film Meet Cute, Kaley Cuoco portrays Sheila, a character facing inner turmoil and contemplating dark thoughts. However, an unexpected twist awaits her as she stumbles upon a remarkable revelation: a tanning bed at a nail salon possesses the incredible ability to transport her back in time by a whole day.Sheila seizes this extraordinary opportunity to relive her cherished date night repeatedly. Yet, as she embarks on this nostalgic journey.

11 Kaley Cuoco As Cassie Bowden In Flight Attendant (2020)

Kaley Cuoco plays the main character, Cassie Bowden, a flight attendant with a seemingly glamorous and carefree lifestyle. However, as the story unfolds, we discover that Cassie's life is far from perfect.

She grapples with alcohol addiction, unresolved trauma, and a series of poor life choices that constantly put her in dangerous situations. Cuoco's portrayal of Cassie is both captivating and raw, as she flawlessly captures the complexities and vulnerabilities of the character. While some questioned if she really was drinking during filming, you can rest assured that she was not, it was all water.

10 Kaley Cuoco As Gretchen Palmer In The Wedding Ringer (2015)

Kaley Cuoco plays the role of Gretchen Palmer, the bride-to-be who is desperately in need of a best man for her upcoming wedding. With no male friends or family members to fill the role, she turns to Jimmy Callahan, played by Kevin Hart, a professional best man-for-hire.

As Gretchen's wedding day approaches, the unlikely duo embarks on a hilarious journey to create the perfect groomsmen squad, leading to a series of laugh-out-loud moments and unexpected twists.

9 Kaley Cuoco As Samantha O’Hare In Hop (2011)

In Tim Hill's 2011 live-action/animated comedy film Hop, Kaley Cuoco plays the part of Samantha. Samantha is a young woman who stumbles upon a mischievous rabbit named E.B., voiced by Russell Brand. As the story unfolds, Samantha finds herself caught up in a whirlwind adventure alongside E.B., who is determined to become a rockstar drummer instead of following in his father's footsteps as the Easter Bunny.

8 Kaley Cuoco As Penny In Big Bang Theory (2007-2019)

Kaley Cuoco's most famous role, of course, is Penny in The Big Bang Theory. Throughout the show, Penny's character experiences a lot of growth and development. She starts off as a struggling actress and waitress and eventually becomes a successful pharmaceutical sales representative.

This growth is not only seen in her career but also in her relationships, as she navigates through various romantic entanglements and ultimately finds love and stability with Leonard. Penny's journey in The Big Bang Theory showcases not only her personal growth but also the evolution of her character's dynamics with the other main characters.

7 Kaley Cuoco As Allyson In To Be Fat Like Me (2007)

In the movie To Be Fat Like Me, Kaley Cuoco plays the role of Allyson, a popular and slender high school student. However, in order to better understand the struggles of her overweight classmates, Allyson decides to disguise herself as a larger girl for a social experiment. As she navigates through the challenges of being overweight, Allyson learns valuable lessons about body image, self-acceptance, and the importance of empathy.

6 Kaley Cuoco As Amanda In Cougar Club (2007)

Kaley Cuoco portrays Amanda in Cougar Club. Her role in this film is that of a young woman who becomes entangled with a group of older women who seek relationships with younger men. Cuoco's character, Amanda, navigates the complexities of this unconventional lifestyle while discovering her own desires and boundaries. Through her performance, Cuoco brings depth and vulnerability to Amanda, showcasing the challenges and growth that come with exploring one's sexuality and defying societal norms.

5 Kaley Cuoco As Katie In Wasted (2006)

In the movie Wasted, Kaley Cuoco plays the role of a young woman named Katie who is struggling with alcohol addiction. Katie's life takes a downward spiral as her addiction begins to consume her, putting strain on her relationships and career. Despite the challenges she faces, Kaley Cuoco's portrayal of Katie showcases the raw emotions and complexities of addiction, shedding light on the harsh realities many individuals face in their battle against substance abuse.

4 Kaley Cuoco As Billie Jenkins In Charmed (2005)

Kaley Cuoco became a part of the final season of Charmed in 2005, portraying the character Billie Jenkins. Initially introduced as a mysterious vigilante, she eventually becomes close to the sisters and receives their guidance. Despite her being incredibly nervous and intimidated to join the show as well as the challenging stunts and special effects involved in her role, Cuoco impressed everyone with her incredible performance and became a beloved character among fans.

3 Kaley Cuoco As Bridget Hennessy In 8 Simple Rules (2002-2005)

Kaley Cuoco's breakout role was in 8 Simple Rules as the daughter, Bridget Hennessey. Kaley's character was that of a typical teenager who struggled with school, dating, and navigating the ups and downs of adolescence.

Her portrayal of Bridget resonated with audiences, showcasing Kaley's talent for bringing relatable characters to life. Sadly, John Ritter, who played her father in the show, passed away unexpectedly during the second season, leaving a void in both the storyline and the hearts of the cast and crew. Despite this tragic loss, Kaley Cuoco continued to shine in her role, honoring Ritter's memory by delivering heartfelt performances that captured the essence of a young girl coping with grief and loss.

2 Kaley Cuoco As Maureen McCormick In Growing Up Brady (2000)

Kaley Cuoco plays Maureen McCormick in Growing Up Brady, a biographical television film based on the memoirs of Barry Williams, who played Greg Brady in the iconic sitcom The Brady Bunch. The film explores the behind-the-scenes dynamics and challenges faced by the cast during the show's production, shedding light on Maureen McCormick's personal journey as well.

1 Kaley Cuoco As Bonnie Stiles In Ladies Man (1999-2001)

In the 1999 sitcom Ladies Man, Kaley Cuoco plays Bonnie Stiles, the daughter of the main character, Leon Phelps. Bonnie is portrayed as a witty and independent young woman who often finds herself caught in the middle of her father's outrageous escapades. Cuoco's performance in Ladies Man showcased her comedic timing and ability to bring charm to her character, solidifying her talent as a rising star in the entertainment industry.